OraTicx announced that it has obtained a patent in recognition of its teeth whitening function as an active ingredient in culture of Oral Probiotics strain oraCMU . This patent acquisition is recognized that hydrogen peroxide produced by the oraCMU is effective in whitening teeth.
OraTicx compared teeth whitening effects by treating artificial teeth stained in coffee solution for 4 weeks in invitro tests in oraCMUTM, 3 lactobacillus-based lactic acid bacteria, 2 Streptococcus-based lactic acid.
As a result of the test, it was found that the whitening effect of artificial teeth treated in a 3% hydrogen peroxide solution and oraCMUTM culture solution was the most excellent.
It showed a big difference from oraCMU treated with lactobacillus, streptococcus lactobacillus, and catalase. In particular, the low whitening effect in oraCMUTM treated with the catalase that decomposes hydrogen peroxide confirms that the hydrogen peroxide produced by oraCMUTMhas a teeth whitening function.
In addition, it was confirmed that the largest amount of hydrogen peroxide was emitted from oraCMUTM culture when seven types of lactic acid bacteria were cultured for 16 hours under 37.7C conditions suitable for probiotics culture.
oraCMUTM was emitted with 9.79 nmol, Lactobacillus family with 4.78 nmol, 2.015 nmol, 0.882 nmol, Streptococcus family with 0.496 nmol, 0.412 nmol, and Weissella family with 6.827 nmol.
oraCMUTM emitted 2 to 11 times more hydrogen peroxide than Lactobacillus and 20 to 24 times more hydrogen peroxide than Streptococcus.
An official from OraTicx has declared that the oral probiotic strain OraCMU has been demonstrated to be effective in preventing and improving oral diseases such as tooth decay, bad breath, and periodontal diseases following seven human trials. Additionally, the official stated that this patent is the first in Korea to utilize oral lactobacillus in order to prevent or delay tooth discoloration.
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